Slide Lots 2 312 Reference Fluid 2 318 Diluents 2 321 Configuring the Diluent Tray 2 323 Immuno-Wash Fluid 2 327 Weekly Maintenance 2 328 Cleaning the Tray Platform and Transport Arm 2 329 Cleaning the Tip-Locator Assembly 2 334 Cleaning the Cup Retainer 2 334 Cleaning the Touchscreen Monitor/Flat LCD Touchscreen Monitor 2 335 Cleaning the Keypad Cover 2 335 Backup QC, Config, and Calibration Data 2 336 Cleaning the Sample-Metering Path 2 337 Inspecting the Air Filter 2 338 As-Required Maintenance 2 339 Replacing Humidity Control Packs and Desiccant Packs 2 342 Changing the Reflectometer Lamp 2 343 Adjusting the Reflectometer Iris 2 349 Replacing the Sample Metering Tubing 2 351 Cleaning the Discard Chutes 2 354 Cleaning the Cabinets 2 355 Cleaning the Dispense Blade/Slide Path 2 357 Cleaning the Incubator Evaporation Caps and Slots 2 362 Replacing the Incubator Evaporation Caps 2 367 Cleaning the Proboscis 2 372 Cleaning the PSID Scanner Window 2 374 Decontaminating the Analyzer 2 374 Cleaning the Analyzer Contents Contents-ii VITROS 250/350 Chemistry System - Operator 9s Manual Version 2.0 3 Diagnostics 3 31 Using the Diagnostics Function 3 33 Mechanism Exercise Diagnostics (MEDS) 3 34 MEDS Sample Handler 3 35 MEDS Sample Handler Movement Sequences 3 37 MEDS Slide Supplies 1 and 2 3 38 MEDS Slide Supplies 1 and 2 Movement Sequences 3 39 MEDS Sample Metering 3 310 MEDS Sample Metering Movement Sequences 4Truck/ Proboscis 3 312 MEDS Sample Metering Movement Sequences 4Pump/ Sample Fluid Drop 3 314 MEDS Reference and Immuno-Rate (IR) Metering 3 315 MEDS Incubator, Transverse Shuttle, and Electrometer 3 316 MEDS Incubator, Transverse Shuttle, and Electrometer Movement Sequences 3 317 MEDS Reflectometer 3 318 Subsystem Tests 3 318 Lab Comp Protocol Analyzer 3 318 Setup/Adjust 3 319 Rate/CM Correction Factor Test 3 329 Reflectometer Iris Adjustment 3 332 Current Setup Values 3 333 Stand-Alone Diagnostic Tests 3 334 Loopback Tests 3 338 Complex Tests 3 338 Performance Tests 3 339 Sample Metering 3 340 Testing Sample Metering Leak/Hysteresis 3 344 Testing Sample Metering Drop Detection 3 349 Incubator 3 349 Testing Incubator Pad Reflectance 3 351 Testing Incubator Position Timing 3 353 PSID Scanner 3 353 Performing the Tool Side Test 3 357 Performing the User Samples Test 3 359 Reflectometer 3 359 Testing the Shutter 3 361 Performing the Reflectometer Static Test 3 366 Running the Dynamic Test 3 372 Reference Metering 3 373 Testing the Reference Fluid Metering Assembly Timing 3 374 Running the System Tests 3 381 Immuno-Rate Metering 3 382 Testing the Immuno-Rate Metering Assembly Timing 3 384 Running the System Tests 3 391 Electrometer 3 392 Testing Electrometer Normal Cycle Version 2.0 VITROS 250/350 Chemistry System - Operator 9s Manual Contents-iii Contents 3 394 Testing Electrometer Contact Drive Timing 3 396 Testing Electrometer Auto Checks 3 3100 Testing Electrometer Extended Auto Checks 3 3102 Cartridge Handling 3 3102 Plunger Count Test 3 3102 Testing the Bar Code Scanner 3 3105 Testing Rotor Movement 3 3108 Hardware and Chemistry Information 3 3110 Recent History Log 3 3113 Condition Code 3 3114 Datalogger Analysis 3 3115 Closing the Current Datalogger File 3 3117 Accessing and Searching Datalogger Files 3 3125 Software Identification 4 Environmental Monitoring 4 31 Environmental Monitoring 4 32 Environmental Error Conditions 4 32 Incubator Temperature Control 4 36 Slide Supply Temperature Control 4 310 Slide Supply Humidity Control 4 315 Voltage Readings 5 Troubleshooting 5 31 Self-Diagnostic Features 5 31 Error Conditions 5 31 Severity Levels 5 33 Error Log Screen 5 37 Troubleshooting Help Screens 5 311 Error Messages for Downloaded Samples 5 311 Flags and Codes on Forms Printer Reports 5 311 Hardware Troubleshooting 5 311 Initializing the Analyzer 5 312 Loading/Resetting (Rebooting) the Analyzer Program 5 312 Clearing Sample Tray Jams 5 315 Clearing Sample Metering Jams 5 316 Clearing Slide Cartridge Jams at the Load Door 5 320 Clearing Slide Cartridge Jams at the Unload Door 5 324 Clearing Slide Cartridge Jams at the Slide Supply Access Door 5 327 Clearing Slide Cartridge and Slide Jams at the Slide Dis- pense Station, the Dispense Blade Path, and the Platen Area 5 336 Clearing Slide Jams in the Transverse Shuttle and at the CM/ RT Eject Blade Position 5 341 Clearing Slide Jams at the Electrometer Discard Station and Contents Contents-iv VITROS 250/350 Chemistry System - Operator 9s Manual Version 2.0 at the PM Slide-Eject Position 5 345 Clearing Slide Jams in the Tip-Locator/Metering Area 5 349 General Troubleshooting Procedures 5 349 Blank Control Unit Monitor 5 349 CRT Monitor 5 349 LCD Monitor 5 349 Touch Screen is not Functioning Properly 5 349 CRT Monitor 5 349 LCD Monitor 5 350 Touch Screen is Visible But Targets Do Not Respond 5 350 CRT and LCD Monitors 5 350 The Analyzer Cannot be Powered Up 5 351 No Results are Printing 5 355 Will Not Upload Data to or Download Data from the Lab Computer 6 Replacing Parts 6 31 Installing a New Slide Supply Rotor Sensor 6 31 Removing the Slide Supply Rotor Sensor 6 34 Replacing the Slide Supply Rotor Sensor 6 37 Replacing a Slide Supply Dispense Blade 6 311 Replacing the Printhead on the Okidata Printer Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide v VITROS 250/350 Chemistry System Maintenance and Diagnostics Manual Revision History Revision Date Description 200 5-01-03 Incorporated updates for the VITROS 250/350 Chemistry System " Reflects software release version 9.0 " Reflects new LCD Monitor " Illustrations reflecting design updates to the Monitor are revised throughout " Added new procedure to clean the LCD Monitor " Updated General Troubleshooting Procedures 04/04 New release. Reflects software version v8.0 " Removed reference to Battery Backup System 10/01 Reflects revised information: " Table of Contents " Daily Maintenance Log (Chapter 2) " Revised Filter Adjustment Guidelines - Target Voltage (Chapter 2) " This manual should contain the following Technical Bulletins: " J12379 - Type III Monitor f or the VITROS 250/250AT, VITROS 550/750 and VITROS 950/950AT Chemistry Systems and VITROS ECi Immunodiagnostic Systems " J12398 - Cleaning Procedure for the TIP Locator Assembly on the VITROS 250/250AT Chemistry System 1/00 Reflects software version 7.0.<br><br> New or revised information: " Revised Filter Adjustment Guidelines (Chapter 3) " Revised Filter Verification Limits (Chapter 3) " Revised replacement blade orientation and illustration (Chapter 6) vi VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions 6/98 Reflects software version 6.0. New or revised information: " Company name change to Ortho-Clinical Diagnostics, Inc., a Johnson & Johnson Company " Revised Safeguards and Precautions " Revised Maintenance Logs (Chapter 2) " Revision to scanner window cleaning procedure (Chapter 2) 9/96 Reflects software version 5.0. New or revised information: " New information for storage of VITROS Reference Fluid reservoirs (Chapter 2) " Addition to proboscis cleaning procedure (Chapter 2) " VITROS Immuno-Wash Fluid on-analyzer storage extended to 72 hours (Chapter 2) " Rate/CM Correction Factor Test screen changes (Chapter 3) " Daily Maintenance Log (Chapter 3) 4/96 Introduction of Johnson & Johnson VITROS Chemistry Systems trade- mark nomenclature.<br><br> 5/95 Reflects software versions 4.0 and higher. New or revised information: " New analyzer label for clearing slide cartridge jams " New periodic maintenance logs (Chapter 2) " Revised reflectometer iris adjustment procedure (Chapters 2, 3) " Information about MEDs targets that will not appear if a subsystem is disabled (Chapter 3) " Revised Rate/CM Correction Factors Test procedure (Chapter 3) " Information about initializing the analyzer with interlocks open (Chapter 5) " New analyzer program load procedure (Chapter 5) " New procedure for clearing slide cartridge jams at the slide supply access door (Chapter 5) " Replacing print heads on the standard Okidata printer (Chapter 6) " Ordering Parts and Sundries (Chapter 7) removed " New index Revision Date Description (Continued) Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide vii Important Safeguards and Precautions 2/1/94 New release. Reflects software version 3.0.<br><br> Table of Contents revised. Revision History and List of Effective Pages added. Change bars used to mark changes since last revision.<br><br> New or revised information: " Preparing for periodic maintenance (Chapter 2) " Periodic maintenance procedures (Chapter 2) 4 Immuno-Wash Fluid maintenance 4 Cleaning the tip locator assembly 4 Adjusting the reflectometer iris 4 Cleaning the dispense blade/slide path 4 Cleaning the incubator evaporation caps and slots 4 Replacing the incubator evaporation caps " Maintenance logs (Chapter 2) " Diagnostics and MEDS (Chapter 3) 4 Rate/CM correction factor test 4 Current setup values 4 Sample metering performance test 4 Immuno-rate metering test " Clearing slide cartridge jams (Chapter 5) " Replacing the slide supply dispense blade (Chapter 6) " Ordering Parts and Sundries (Chapter 7) 1/1/93 First release of manual. Reflects version 1.1 of the software Revision Date Description (Continued) viii VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions VITROS 250/350 System Maintenance and Diagnostics Manual List of Effective Pages . Publication Date Section Page 200 5-01-03 All pages in this publication have been revised to reflect Version 2.0 04/04 All pages in this publication have been revised to reflect Version 1.0 Important Safeguards and Precautions Page xviii Chapter 1 - Welcome Page 1-1 Chapter 2 - Periodic Maintenance Page 2-6 - 2-9, 2-11, 2-20 Chapter 3- Diagnostics Page 3-126 Chapter 5 - Troubleshooting Page 5-1 10/01 Contents Pages i-iii Chapter 2 - Periodic Maintenance Pages 46, Daily Maintenance Log 1/00 All pages listed below should be at publication date 1/00.<br><br> Chapter 3 - Diagnostics Pages 31-32 Chapter 6 - Replacing Parts Page 9 6/98 All pages listed below should be at publication date 6/98. Important Safeguards and Precautions Pages viii, xviii Chapter 2 - Periodic Maintenance Maintenance Logs Pages 71-74 Chapter 3 - Diagnostics All pages Chapter 4 - Environmental Monitoring Page 1 9/96 All pages listed below should be at publication date 9/96. All other pages should be at publication date 5/95.<br><br> Reprinted 4/96 or 2/1/94. Reprinted 4/96. Chapter 2 - Periodic Maintenance All pages Daily Maintenance Log Chapter 3 - Diagnostics Pages 21-22 5/95 All pages listed below should be at publication date 5/95.<br><br> All other pages should be at publication date 2/1/94. Reprinted 5/95. Important Safeguards and Precautions Pages iii 3vi, x, xi Contents All pages Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide ix Important Safeguards and Precautions Chapter 2 - Periodic Maintenance Pages 45, 45.a, 45.b, 46, Maintenance Logs Chapter 3 - Diagnostics Pages 4, 14, 15, 19, 20, 21- 23, 23.a, 23.b, 23.c, 23.d, 24, 25, 25.a, 25.b, 26 Chapter 5 - Troubleshooting Pages 7, 13, 14, 25, 25.a, 25.b, 25.c, 25.d Chapter 6 - Replacing Pages Pages 11-14 Chapter 7 Removed Index All pages 2/1/94 All sections All pages Publication Date Section Page x VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions Laser Light Warning Important Safeguards and Precautions Laser Light Warning The VITROS 250/350 Chemistry System, with Positive Sample Identification (PSID) installed, uses a Class II Visible Laser Diode that emits a low-power laser beam.<br><br> Brief eye exposure to the beam will not cause any known biological harm, but you should not stare directly into the laser beam, just as you would not stare at the sun. Use caution to avoid exposing your eyes to a reflection of the laser beam. Do not place any reflecting surface in the path of the beam when the equipment is in operation.<br><br> Only qualified service personnel should perform alignments, adjustments, and disassembly procedures. Use of controls, adjustments, or procedures other than those specified in this manual may result in hazardous radiation exposure. The following warning appears in the Reference Set.<br><br> Laser Light Safety Label The laser light safety label is located on the PSID scanner. WARNING Avoid directly and continually exposing your eyes to the laser beam, or a reflection of the laser beam. LASER RADIATION IS EMITTED FROM THIS APERTURE CAUTION 3 LASER RADIATION WHEN OPEN DO NOT STARE INTO BEAM.<br><br> CLASS 2 LASER PRODUCT AVOID LONG TERM VIEWING OF DIRECT LASER RADIATION Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide xi Important Safeguards and Precautions Electrical Hazards Electrical Hazards Potential electrical hazards exist behind the side, front, and back panels. Keep doors, covers, and panels closed during normal operation for your own protection and to maintain analyzer temperature. Do not operate the analyzer if any of the modules have been removed.<br><br> Removing modules from their normal positions may create electrical hazards. This includes slide supply, sample metering, sample handler (tip supply, mixing cup supply, tray transport, sample supply, diluent supply), reference fluid metering, incubator, reflectometer, and electrometer modules. Scanner Safeguards The scanner component used for Positive Sample Identification (PSID) is an integral part of the system.<br><br> Only qualified service personnel should perform alignments, adjustments, and disassembly procedures of the PSID scanner component. xii VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions Analyzer Labels Analyzer Labels Listed below are the agency-approved, warning, safety, and miscellaneous labels on the analyzer. Illustrations showing their location follow.<br><br> " Name Plate: Sample Handler " Name Plate: Slide Processor " Slide Supply 4 Analyzer Options 4 Hardware Modifications: Slide Processor 4 Clearing Slide Cartridge Jams " Hardware Modifications: Sample Handler " Reset " Biohazard (Slide Disposal Box) " Biohazard (Mixing Cup Array and Tip Disposal Box) " Cartridge Disposal Box " Ground Symbol " Hot Surface (Lamp) " Hot Surface " Refer to Manual " Volume Control/Iris Adjustment " Laser Compliance " Laser Light Safety " Leakage Current " FCC " CDOC (Canadian) " VFG (Verflugen) " High Voltage " 120-Volt Printer " 120-Volt Monitor " Ports " Mechanical Pinch Point " Rotor Assembly Disk " Electrolyte Reference Fluid (ERF) " Immuno-Wash Fluid (IWF) Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide xiii Important Safeguards and Precautions Analyzer Labels Name Plate: Sample Handler Name Plate: Slide Processor Slide Supply: 3 Analyzer Options 3 Hardware Modifications: Slide Supply 3 Clearing Slide Cartridge Jams Made in Germany for Ortho-Clinical Diagnostics, Inc. Rochester, New York 14626-5101 SERIAL NUMBER SERVICE CODE 50/60Hz 12A 3331 50/60Hz 6A 100 - 120V~ 200 - 240V~ 2505 LISTED R 3D90 R TÜV Rheinland geprüfte Sicherheit CLASSIFICATION Made by Ortho-Clinical Diagnostics, Inc. Rochester, New York 14626-5101 SERIAL NUMBER SERVICE CODE 3332 2501XXXX CnP xiv VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions Analyzer Labels Hardware Modifications: Sample Handler Reset Biohazard (Slide Disposal Box) HARDWARE MODIFICATION KODAK Program Load / Reset Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide xv Important Safeguards and Precautions Analyzer Labels Biohazard (Mixing Cup Array and Tip Disposal Box) Cartridge Disposal Box Ground Symbol xvi VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions Analyzer Labels Hot Surface (Lamp) Hot Surface Refer to Manual Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide xvii Important Safeguards and Precautions Analyzer Labels Volume Control/Iris Adjustment Laser Compliance (only with PSID installed) Laser Light Safety (only with PSID installed) Ortho-Clinical Diagnostics Rochester, NY 14626-5101 LASER RADIATION IS EMITTED FROM THIS APERTURE CAUTION 3 LASER RADIATION WHEN OPEN DO NOT STARE INTO BEAM.<br><br> CLASS 2 LASER PRODUCT AVOID LONG TERM VIEWING OF DIRECT LASER RADIATION xviii VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions Analyzer Labels Leakage Current FCC CDOC (Canadian) CAUTION HIGH LEAKAGE CURRENT ENSURE PROPER GROUNDING ATTENTION COURANT DE FUITE ÉLEVÉ FOURNIR UNE MISE A LA TERRE EFFICACE This device complies with Part 15 of the FCC Rules. Operation is subject to the following two conditions: (1) This device may not cause harmful interference, and (2) this device must accept any interference received, including interference that may cause undesired operation. Le présent apparell numérique n 9émet pas de brulis radio- électriques dépas- sant les limites appli- cables aux apparells numériques de la classe B prescrites dans le Réglement sur le brouillage ra- dioélectrique édicté par le ministére des Communications du Canada.<br><br> This digital apparatus does not exceed the Class B limits for radio noise emissions from digital apparatus set out in the Radio Interference Reg- ulations of the Canadian Depart- ment of Communi- cations. PN 356409 Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide xix Important Safeguards and Precautions Analyzer Labels High Voltage 120-Volt Printer 120-Volt Monitor Ports xx VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions Analyzer Labels Mechanical Pinch Point Rotor Assembly Disk Electrolyte Reference Fluid (ERF) Immuno-Wash Fluid (IWF) Inside Top View ATTENTION After removing the rotor assy, place the label side down to protect the surface of the disk. ERF IWF Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide xxi Important Safeguards and Precautions General Precautions General Precautions We recommend that the key operator perform all periodic maintenance procedures.<br><br> Moving Parts Wherever there are moving parts, such as the dispense blade, slide supply rotors, and the incubator disk, use caution when correcting malfunctions and when operating the analyzer. When either of the covers of the VITROS 250/350 Chemistry System are raised, interlock switches prevent the movement of any high-speed or high-power modules. Other modules are still operational.<br><br> Cleaning Solutions Do not use any solvents or cleaning solutions on the equipment other than distilled or deionized water. Never use ammonia cleaners on or near the analyzer. CAUTION: Do not use solvents, alcohol, ammonia, glass cleaners, or cleaning agents containing abrasives to clean the control unit monitor.<br><br> These items will damage the touch screen and impair your ability to inter- act with the analyzer computer. CAUTION: Do not use solvents, alcohol, ammonia, glass cleaners, or cleaning agents containing abrasives to clean the incubator evaporation caps. These items will damage the caps and affect system performance.<br><br> CAUTION: Do not touch or clean the Spectralon reference material. WARNING: Dispose of paper towels and cotton swabs used to clean the analyzer following biohazard procedures. These items may be contaminated with serum or other body fluids.<br><br> Clean contaminated analyzer components using a 70 percent isopropyl alcohol in water solution when suggested in the following maintenance procedures. Be sure to use no more than a 70 percent concentrated solution. It is critical that enough water is present to hydrolyze and thus break down proteins.<br><br> NOTE: Do not contaminate any other fluids (for example, VITROS 250/350 System Reference Fluid) with isopropyl alcohol solution. NO fluids used on the analyzer should be contaminated with isopropyl alcohol solution or erroneous results will occur. Rinse all components thoroughly with warm distilled or deionized water to remove all traces of isopropyl alcohol.<br><br> Do not autoclave any component unless autoclaving is specifically indicated to be an acceptable alternative. NOTE: You may leave the analyzer on, unless specified otherwise; but do not process samples while you perform maintenance procedures. Moving the Equipment Only authorized field personnel are permitted to move equipment from one location to another.<br><br> If the equipment is moved, it should be checked by authorized personnel. The equipment should also be checked if any unusual vibration has occurred that may affect it (for example, heavy construction nearby or earthquake). xxii VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Important Safeguards and Precautions Moving the Equipment Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 1 31 1 Welcome The VITROS 250/350 Chemistry System will provide optimum performance when you use it according to recommended operating and periodic maintenance instructions.<br><br> (See the Operator 9s Manual and the Quick Guide of the Reference Set for the operating instructions, and Chapter 2, cPeriodic Maintenance d in this volume.) Be sure to perform all daily, weekly, and as-required maintenance procedures to keep your equipment running efficiently and to ensure reliable results. Sample maintenance logs are provided at the end of Chapter 2 for your convenience. Complete a maintenance log each time you perform maintenance procedures.<br><br> Should you encounter any difficulties in daily operation of the equipment, consult Chapter 3, cDiagnostics, d or Chapter 5, cTroubleshooting, d in this volume. Should you encounter further difficulties, contact your Customer Support Representative for assistance. Welcome 1 32 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 31 2 Periodic Maintenance Preparing for Periodic Maintenance This chapter provides you with information for maintaining the VITROS 250/350 Chemistry System.<br><br> It is divided into three parts 4daily, weekly, and as-required maintenance. NOTE: You may leave the analyzer on, unless specified otherwise; but do not process samples while you perform maintenance procedures. After performing each maintenance procedure, make a record of it on a maintenance log.<br><br> There are sample logs at the end of this chapter and in the Operator 9s Quick Guide. You may copy them for your use, or you may want to establish a customized maintenance log for your own laboratory. If questions arise on maintenance and diagnostics during daily operation of the analyzer, read the manual carefully.<br><br> If you still need assistance, contact your Customer Support Representative. WARNING: Assume that all used equipment is contaminated with potentially infectious biological material. Use the cUniversal Precautions d rec- ommended by OSHA (Occupational Safety and Health Administra- tion) Bloodborne Pathogen Standard 29CFR1910.1030 when handling or cleaning equipment.<br><br> In particular: "Wear gloves, closed shoes, buttoned lab coats, and safety glasses throughout the cleaning and maintenance process. "Treat all waste materials used in the cleaning process as contaminated. Follow the site procedures for your laboratory to dispose of these materials.<br><br> "Handle all equipment with care. Mechanical parts may have edges, pinch points, and corners that could potentially cause injury. Refer to the cImportant Safeguards and Precautions d at the beginning of this manual for more information.<br><br> In addition, refer to the NCCLS guidelines for cProtection of Laboratory Workers from Instrument Biohazards d (NCCLS Document M29-A). Periodic Maintenance Preparing for Periodic Maintenance 2 32 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 To access the Periodic Maintenance screen and begin using the periodic maintenance features, touch PERIODIC MAINTENANCE on the Main Menu. Instructions on using the daily, weekly, and as-required maintenance features follow.<br><br> Apr 24 XX 14:13:12 VX.XX**250 READY LAB COMP : TESTING COMPLETE SAMPLING OFF ON PM00A HELP RETURN PERIODIC MAINTENANCE > Touch a target to select a category. DAILY MAINTENANCE WEEKLY MAINTENANCE AS REQUIRED MAINTENANCE Categories: REMOTE ENABLED Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 33 Periodic Maintenance Daily Maintenance Daily Maintenance Perform daily maintenance each day before processing samples. Disposals and Supplies To perform daily maintenance for disposals and supplies: 1.<br><br> Touch DAILY MAINTENANCE on the Periodic Maintenance screen. 2. Touch DISPOSALS AND SUPPLIES.<br><br> 3. Perform the daily maintenance procedures shown on the screen. Instructions follow.<br><br> Apr 24 XX 14:13:12 VX.XX**250 READY LAB COMP: TESTING COMPLETE SAMPLING OFF ON PM00B HELP RETURN PERIODIC MAINTENANCE - Daily > Touch a target to select a category. DISPOSALS AND SUPPLIES FLUIDS Categories Apr 24 XX 14:13:12 VX.XX**250 READY LAB COMP: TESTING COMPLETE SAMPLING OFF ON PM00C HELP RETURN EMPTY: 1. Mixing Cup and Tip Disposal Container.<br><br> 2. Slide Cartridge Disposal Container. 3.<br><br> Slide Disposal Container. INSPECT: 1. Sample Trays for cleanliness/damage.<br><br> LOAD: 1. Mixing Cup Array in the Cup Supply. 2.<br><br> Tips in the Tip Supply. VERIFY: 1. Slide Inventory on the Analyzer.<br><br> 2. QC Fluids are run on Slide Lots to be used. PERIODIC MAINTENANCE - Daily Periodic Maintenance Emptying Disposal Boxes 2 34 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Emptying Disposal Boxes There are three disposal boxes located behind the two front doors of the analyzer.<br><br> You must empty them daily. NOTES:Be sure testing is complete and sampling is OFF before you empty the disposal boxes. The analyzer does not prevent removal of the boxes while tests are in process.<br><br> If the mixing- cup array and tip disposal box is removed while sampling is on or if the slide-disposal box is removed while tests are in process, the disposal box tracks may become contaminated. The slide disposal box holds approximately 800 slides. High- volume laboratories may need to empty the box more often than once a day.<br><br> Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 35 Periodic Maintenance Emptying Disposal Boxes To empty the disposal boxes: 1. Open the two front doors of the analyzer. 2.<br><br> Remove the three disposal boxes (the mixing cup array and tip disposal box, the slide disposal box, and the cartridge disposal box) from the analyzer. 3. The mixing cup array and tip disposal box and the slide disposal box contain liners.<br><br> Discard the two liners and their contents following your established laboratory procedures for the disposal of biohazardous materials. Slide-Disposal Box Cartridge-Disposal Box Mixing-Cup Array and Tip-Disposal Box Periodic Maintenance Emptying Disposal Boxes 2 36 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 4. Discard the contents of the cartridge disposal box according to your laboratory 9s procedures.<br><br> The cartridge disposal box does not receive biohazardous waste. 5. If any of the disposal boxes are contaminated with body fluids, clean them as follows: 4 Clean the boxes using 70 percent isopropyl alcohol in water solution.<br><br> 4 Rinse the boxes thoroughly with warm water. 4 Allow the boxes to air dry thoroughly. 6.<br><br> Place a new liner in the slide disposal box. Use a Slide Disposal Box Liner, Cat. No.<br><br> 120-4791. 7. Reinsert the slide disposal box into the analyzer.<br><br> Push the disposal box as far as possible to the rear of the analyzer. 8. Place a new liner in the mixing-cup array and tip disposal box.<br><br> Use a VITROS Disposal Box Liner CM/Cup Array, Cat. No. 125-0273.<br><br> 9. Reinsert the mixing cup array and tip disposal box into the analyzer. Push the disposal box as far as possible to the rear of the analyzer.<br><br> 10. Reinsert the cartridge disposal box. This box does not receive biohazardous waste; therefore, it does not require a liner.<br><br> 11. Close the two front doors. Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 37 Periodic Maintenance Cleaning Sample Trays Cleaning Sample Trays Inspect the sample trays for any damage such as cracks or missing parts.<br><br> Using damaged trays can result in sample metering problems. Replace them, if necessary. To clean the sample trays: 1.<br><br> Wash soiled trays in warm, soapy water. 2. Rinse with water to remove any soap residue.<br><br> 3. Clean contaminated trays using 70 percent isopropyl alcohol in water solution. 4.<br><br> Rinse the trays thoroughly with warm water. 5. Allow the trays to air dry thoroughly.<br><br> Do not autoclave the trays. Universal Sample Tray Periodic Maintenance Cleaning Height, Cup, and PCS Microcollection Tube Adapters 2 38 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Cleaning Height, Cup, and PCS Microcollection Tube Adapters To clean height, cup, and tube adapters: 1. Wash soiled adapters in warm, soapy water.<br><br> 2. Rinse with water to remove any soap residue. 3.<br><br> Clean contaminated adapters using 70 percent isopropyl alcohol in water solution. 4. Rinse the adapters thoroughly with warm water.<br><br> 5. Allow the adapters to air dry thoroughly. Do not autoclave the adapters.<br><br> Universal Sample Tray Cup Adapter Height Adapter Microcollection Tube Adapter Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 39 Periodic Maintenance Loading Mixing Cup Arrays and Tips Loading Mixing Cup Arrays and Tips To load mixing-cup arrays and sample tips: 1. From the front of the analyzer, slide the mixing cup arrays onto the transport belt of the mixing cup array supply. The supply holds a maximum of five trays.<br><br> 2. Place the VITROS VersaTips into the Tip Rack. 3.<br><br> Load the tip rack onto the transport belts of the tip supply. The supply holds a maximum of four racks. Periodic Maintenance Verifying Slide Inventory 2 310 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Verifying Slide Inventory You can use the slide inventory feature to display the total number of slides loaded for each test and lot number.<br><br> This daily step allows you to evaluate slide inventory and manage slide lots, keep an adequate supply of calibrated slides on the analyzer to avoid unnecessary stops during sample processing, and know when a slide lot will run out to plan calibration or quality control. When you transfer data from a new calibration diskette, the new diskette may not support some of the slides currently loaded on the analyzer if their generations have expired. These slides will not appear on the Slide Inventory screen.<br><br> To verify slide inventory on the analyzer: 1. Press the (F2) function key on the keyboard to display the Cartridge Handling dialogue. 2.<br><br> Touch SLIDE INVENTORY in the Display column 14:13:12 VX.XX**250 OFF ON CH01A CARTRIDGE HANDLING Unload: ALL EMPTY CARTRIDGES BY POSITION BY TEST / LOT ALL CARTRIDGES BY SUPPLY SLIDE SUPPLY CONTENTS Display: BY POSITION MANUAL LOT # ENTRY Load: NEW GEN SLIDE INVENTORY Nov 02 92 READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Touch a target to select a function. Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 311 Periodic Maintenance Verifying QC Fluids are Run on Slide Lots 3. Compare the total number of slides available against what you anticipate needing for your daily run.<br><br> 4. Touch RETURN twice to return to Periodic Maintenance. Verifying QC Fluids are Run on Slide Lots Check and verify that quality control fluids have been run on the slide lots you will be using.<br><br> Run quality control fluids as part of your daily maintenance after performing all other daily maintenance procedures. Minimum frequency for monitoring the performance of the analyzer and slides is once every 24 hours. (State and/or local regulations may require more frequent performance checks.) For a detailed explanation of the quality control feature, refer to Chapter 11, cQuality Control, d in the Operator 9s Manual.<br><br> 14:13:12 VX.XX**250 CH01B CARTRIDGE HANDLING - Inventory PAGE 1 of 4 Test : ALB AMYL CHOL (HDLC) Cl- ECO2 GLU K+ Na+ TP TRIG URIC dHDL Total Slide Count : Lot Number : 0832-4655 4003-4566 PRINT INVENTORY NEXT PAGE PREVIOUS PAGE > Touch NEXT PAGE for more inventory data. Touch PRINT INVENTORY to print the inventory data. 49 54 51 52 57 0 46 48 50 57 57 46 Cal'd Fluid: S/U S/U S/U Current : S S OFF ON Jul 15 92 READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN S 1191-1111 S S S 0928-5384 6015-2964 5707-2659 0512-3589 0722-2934 0635-4124 4223-43481 4102-7161 S S/U S S S S/U S S/U S/U S S S S/U Periodic Maintenance Reference Fluid 2 312 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Reference Fluid To perform the daily maintenance procedure for reference fluid: 1.<br><br> Lift the top right cover of the analyzer. 2. Touch PERIODIC MAINTENANCE on the Main Menu.<br><br> 3. Touch DAILY MAINTENANCE. 4.<br><br> Touch FLUIDS. Apr 24 XX 14:13:12 VX.XX**250 READY LAB COMP: TESTING COMPLETE SAMPLING OFF ON PM00B HELP RETURN PERIODIC MAINTENANCE - Daily > Touch a target to select a category. DISPOSALS AND SUPPLIES FLUIDS Categories Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 313 Periodic Maintenance Reference Fluid 5.<br><br> Touch REFERENCE FLUID. The reference metering arm will lift out of the reservoir to the tip-change position. The screen instructs you to change the tip and the reservoir.<br><br> 14:13:12 VX.XX**250 OFF ON PM00D REFERENCE FLUID DILUENTS Fluids: IMMUNO- WASH FLUID PERIODIC MAINTENANCE - Daily Aug 23 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Touch a target to select a fluid. Periodic Maintenance Reference Fluid 2 314 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 NOTE: You must change the VITROS Micro Tip every eight hours. You must change the Reference Fluid Reservoir and clean the reference fluid reservoir cover seal every 24 hours.<br><br> Bring a fresh, unopened disposable reservoir to analyzer temperature before use. Do this by placing the reservoir on top of the incubator cover for a minimum of 30 minutes. An unrefrigerated reservoir is stable for 24 hours.<br><br> Reservoirs that will not be used right away should remain refrigerated. 14:13:12 VX.XX**250 OFF ON PM00E PERIODIC MAINTENANCE - Daily Immuno-Wash Fluid: 1. Change Tip.<br><br> 2. Change Reservoir. CURRENT RESERVOIR DROP COUNT VALUE: 258 May 19 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Was the fluid reservoir replaced?<br><br> NEW RESERVOIR DROP COUNT VALUE: 300 (Y/N): Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 315 Periodic Maintenance Reference Fluid 6. Swing up the arm so that it forms a right angle with the reference- metering assembly. 7.<br><br> With one hand, pull the lever to eject the tip. Be prepared to catch the tip with your other hand as it ejects. 8.<br><br> Wipe the reference proboscis (which holds the VITROS Micro Tip in place) with a lint-free cloth moistened with distilled or deionized water. 9. Dry it with another lint-free cloth.<br><br> 10. Steady the arm with one hand. Insert a new micro tip by pushing it firmly into place.<br><br> You will hear a click. Reference Metering Arm Reference Metering Assembly Lever VITROS Micro Tip Periodic Maintenance Reference Fluid 2 316 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 11. Replace the reservoir.<br><br> 4 Lift the retainer lid that holds the reservoir. 4 Remove the old reservoir and discard it. 4 Wipe out the housing using a lint-free cloth.<br><br> 4 Mix the reservoir thoroughly by gentle inversion. 4 Peel the protective seal off the reservoir after it has reached room temperature. 4 Place the reservoir into the reservoir housing.<br><br> WARNING: Do not place the reference fluid reservoir into the Immuno-Wash Fluid reservoir housing. Error codes may occur during immuno-rate Sample Processing. 12.<br><br> Remove the reference fluid reservoir cover. 13. Remove the seal from the bottom of the reservoir cover, and clean it with distilled or deionized water.<br><br> Reference Fluid Reservoir Housing Cover BOTTOM OF RESERVOIR COVER Seal Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 317 Periodic Maintenance Reference Fluid 14. Wipe the cover with a lint-free cloth moistened with distilled or deionized water. 15.<br><br> Dry the cover and seal thoroughly, being careful not to leave any lint or fibers. 16. Insert a clean seal on the cover, and return the cover to its normal operating position.<br><br> 17. Type cY d and press the Enter key on the keyboard to answer the prompt, cWas the fluid reservoir replaced? d 18. Touch RETURN.<br><br> The reference arm assembly will return to the chome d position, and the screen will display the fluid drop count update. 19. Touch RETURN.<br><br> The analyzer will initialize. 14:13:12 VX.XX**250 OFF ON PM00E PERIODIC MAINTENANCE - Daily Immuno-Wash Fluid: 1. Change Tip.<br><br> 2. Change Reservoir. CURRENT RESERVOIR DROP COUNT VALUE: 258 May 19 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Was the fluid reservoir replaced?<br><br> NEW RESERVOIR DROP COUNT VALUE: 300 (Y/N): Periodic Maintenance Diluents 2 318 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Diluents NOTE: Fresh diluent fluids must be at room temperature. See the VITROS Instructions for Use for on-board stability. To perform daily maintenance for diluents: 1.<br><br> Touch FLUIDS on the Periodic Maintenance 3 Daily screen. 2. Touch DILUENTS.<br><br> The diluent tray carrier is moved toward the front of the analyzer. 3. Remove the tray through the diluent supply opening in the front of the analyzer.<br><br> 14:13:12 VX.XX**250 OFF ON PM00D REFERENCE FLUID DILUENTS Fluids: IMMUNO- WASH FLUID PERIODIC MAINTENANCE - Daily Aug 23 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Touch a target to select a fluid. Diluent Supply Opening Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 319 Periodic Maintenance Diluents 4. Remove the old diluents, if any, and discard them.<br><br> We supply 7% BSA/Bovine Serum Albumin and VITROS Urine Electrolyte Diluent in glass bottles designed to fit onto the diluent tray. It may be advantageous to transfer aliquots of these diluents to 2 mL sample cups (without caps). Simply put the cup onto the diluent tray, and the tray 9s stopper will prevent evaporation.<br><br> Several empty bottles are provided for distilled water and saline. NOTE: The seven percent BSA and the Urine Electrolyte Diluents can remain on the diluent tray no longer than seven days. 5.<br><br> Remove and clean the rubber stoppers every time a bottle is removed or inserted. Replace any stoppers that are cracked or damaged. 14:13:12 VX.XX**250 OFF ON PM00F 1.<br><br> Place fluids in positionas shown. 2. Load Diluent Tray on the Analyzer.<br><br> PERIODIC MAINTENANCE - DAILY Diluent Configuration - Tray A 2ml 2ml 2ml 2ml 5ml 5ml 10ml 10ml PAT PAT SALN ABSA SPEC 7BSA H20 ELEC 1 2 3 4 5 6 7 8 Apr 24 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Touch RETURN to reload the Diluent Tray. Stopper Periodic Maintenance Diluents 2 320 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 NOTE: Wear clean gloves when you clean and replace the stoppers to prevent finger oil or contaminated gloves from contaminating the stoppers. 6.<br><br> Locate a new stopper. The stoppers have two grooves on the top surface. Hold the stopper flat side down, and insert the top groove into the gap on the diluent tray stopper holder.<br><br> 7. After replacing as many stoppers as required, place fresh, room- temperature diluent fluids in positions shown on the screen. 8.<br><br> Load the diluent tray back onto the diluent tray carrier. 9. Touch RETURN, and the diluent tray will return automatically to its chome d position.<br><br> 14:13:12 VX.XX**250 OFF ON PM00F 1. Place fluids in positionas shown. 2.<br><br> Load Diluent Tray on the Analyzer. PERIODIC MAINTENANCE - DAILY Diluent Configuration - Tray A 2ml 2ml 2ml 2ml 5ml 5ml 10ml 10ml PAT PAT SALN ABSA SPEC 7BSA H20 ELEC 1 2 3 4 5 6 7 8 Apr 24 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Touch RETURN to reload the Diluent Tray. Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 321 Periodic Maintenance Configuring the Diluent Tray Configuring the Diluent Tray To configure the diluent tray if the current configuration does not meet your needs: 1.<br><br> Touch OPTIONS on the Main Menu. 2. Type the access code using the keyboard, and press the Enter key on the keyboard.<br><br> 3. Touch ANALYZER CONFIG in the System Services column. 4.<br><br> Touch DILUENT TRAY CONFIG in the Tests column. Jul 15 92 14:13:12 VX.XX**250 READY LAB COMP : TESTING COMPLETE SAMPLING OFF ON OP00B > Touch a target to select an option. HELP RETURN OPTIONS System Services SUBSYSTEM CONTROL ANALYZER CONFIG SPECIAL SERVICES REPORT CONTROL WORKLOAD & USAGE REPORTS Disk Srvcs LOAD CAL DISKETTE DISK FILE SERVICES BACKUP/ RESTORE DISKETTE Cal Data CAL PARAMS CALIBRATOR SAVs CALIBRATOR LOT # SELECTION Test Data TEST/ FLUID CONFIG DILUENT DATA COEF & LIMITS ADDITIONAL TESTS CONFIG PRINT CONFIG REPORT Jul 15 92 14:13:12 VX.XX**250 READY LAB COMP : TESTING COMPLETE SAMPLING OFF ON OP00E > Touch a target to select a category.<br><br> HELP RETURN OPTIONS 3 Analyzer Configuration Memory LANGUAGE CONFIG SAMPLE PROGRAM RETENTION RESULT RECORD RETENTION Reports Tests DILUENT TRAY CONFIG TEST REPORTING CONFIG Functions STATUS CONSOLE ANALYZER NAME CONFIG LAB COMPUTER CONFIG PATIENT REPORT CONFIG LAB REPORT CONFIG PRINTER REPORT CONFIG Periodic Maintenance Configuring the Diluent Tray 2 322 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 5. To add diluents or to change the current diluent tray setup, touch a diluent tray position target. 6.<br><br> Type the diluent name abbreviation (up to four characters) desired in that position, and press the Enter key on the keyboard. 7. Touch another tray position target to continue updating the diluent tray configuration.<br><br> 8. To cancel any changes made, touch RETURN. 9.<br><br> To save the updated configuration, touch ENTER TRAY CONFIG. 10. Touch RETURN to exit.<br><br> Aug 24 XX 14:13:12 VX.XX**250 READY LAB COMP : TESTING COMPLETE SAMPLING OFF ON OP31Q > To add diluents or to change the current tray setup, touch a tray postion; type diluent name desired in that position, then press ENTER. HELP RETURN OPTIONS 3 Analyzer Configuration ENTER TRAY CONFIG Diluent Tray Configuration Diluent Configuration 3 Tray A 2ml 2ml 2ml 2ml 5ml 5ml 10ml 10ml PAT PAT SALN ABSA H20 H20 7BSA ELEC 1 2 3 4 5 6 7 8 Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 323 Periodic Maintenance Immuno-Wash Fluid Immuno-Wash Fluid To perform daily maintenance for immuno-wash fluid: 1. Touch FLUIDS on the Periodic Maintenance-Daily screen.<br><br> 2. Touch IMMUNO-WASH FLUID. 14:13:12 VX.XX**250 OFF ON PM00D REFERENCE FLUID DILUENTS Fluids: IMMUNO- WASH FLUID PERIODIC MAINTENANCE - Daily Aug 23 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Touch a target to select a fluid.<br><br> 14:13:12 VX.XX**250 OFF ON PM00E PERIODIC MAINTENANCE - Daily Immuno-Wash Fluid: 1. Change Tip. 2.<br><br> Change Reservoir. CURRENT RESERVOIR DROP COUNT VALUE: 258 May 19 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Was the fluid reservoir replaced? NEW RESERVOIR DROP COUNT VALUE: 300 (Y/N): Periodic Maintenance Immuno-Wash Fluid 2 324 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 NOTE: You must change the VITROS Micro Tip every eight hours.<br><br> You must change the Immuno-Wash Fluid Reservoir at least every 72 hours, and clean the reservoir cover seal every 24 hours. Bring a fresh, unopened disposable reservoir to analyzer temperature before use. Do this by placing the reservoir on top of the incubator cover for a minimum of 30 minutes before use.<br><br> Return any unopened reservoirs to the refrigerator if you will not use them immediately. 3. Swing up the arm so that it forms a right angle with the immuno- rate metering assembly.<br><br> 4. With one hand, pull the lever to eject the tip. Be prepared to catch the tip with your other hand as it ejects.<br><br> Immuno-Rate Metering Arm Immuno-Rate Metering Assembly Lever VITROS Micro Tip Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 325 Periodic Maintenance Immuno-Wash Fluid 5. Wipe the immuno-rate proboscis (which holds the VITROS Micro Tip in place) with a lint-free cloth moistened with distilled or deionized water. 6.<br><br> Dry it with another lint-free cloth. 7. Steady the arm with one hand.<br><br> Insert a new micro tip by pushing it firmly into place. You will hear a click. 8.<br><br> Replace the reservoir. 4 Lift the IR metering arm. 4 Lift the retainer lid that holds the reservoir.<br><br> 4 Remove the old reservoir and discard it. 4 Wipe out the housing using a lint-free cloth. 4 Mix the reservoir thoroughly by gentle inversion.<br><br> 4 Peel the protective seal off the top of the reservoir after it has reached room temperature. 4 Place the reservoir into the reservoir housing. The reservoir will have a yellow label and the housing will have a yellow dot.<br><br> WARNING: Do not place the Immuno-Wash Fluid reservoir into the reference fluid reservoir housing. Biased electrolyte results may occur. 9.<br><br> Remove the wash fluid reservoir cover. Immuno-Wash Fluid Reservoir Cover Housing Periodic Maintenance Immuno-Wash Fluid 2 326 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 10. Remove the seal from the bottom of the reservoir cover, and clean it with distilled or deionized water.<br><br> 11. Wipe the cover with a lint-free cloth moistened with distilled or deionized water. 12.<br><br> Dry the cover and seal thoroughly, being careful not to leave any lint or fibers. 13. Insert a clean seal on the cover, and return the cover to its normal operating position.<br><br> 14. Type cY d and press the Enter key on the keyboard to answer the prompt, cWas the fluid reservoir replaced? d 15. Touch RETURN.<br><br> The immuno-rate arm assembly will return to the chome d position, and the screen will display the fluid drop count update. 16. Touch RETURN.<br><br> The analyzer will initialize. BOTTOM OF RESERVOIR COVER Seal 14:13:12 VX.XX**250 OFF ON PM00E PERIODIC MAINTENANCE - Daily Immuno-Wash Fluid: 1. Change Tip.<br><br> 2. Change Reservoir. CURRENT RESERVOIR DROP COUNT VALUE: 300 May 19 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Was the fluid reservoir replaced?<br><br> NEW RESERVOIR DROP COUNT VALUE: 300 (Y/N): Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 327 Periodic Maintenance Weekly Maintenance Weekly Maintenance To display the weekly maintenance procedures: 1. Touch PERIODIC MAINTENANCE on the Main Menu. 2.<br><br> Touch WEEKLY MAINTENANCE. 3. Perform the weekly maintenance procedures displayed on the screen.<br><br> Instructions follow. 14:13:12 VX.XX**250 OFF ON PM00H CLEAN: 1. Tray platform and transport arm.<br><br> 2. Tip locator assembly. 3.<br><br> Cup retainer. 4. Control unit screen / keypad cover.<br><br> INSPECT: 1. Sample Metering path for cleanliness. 2.<br><br> Air filter. Apr 24 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN PERIODIC MAINTENANCE - Weekly Periodic Maintenance Cleaning the Tray Platform and Transport Arm 2 328 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Cleaning the Tray Platform and Transport Arm To clean the tray platform and transport arm: 1. Lift the top left cover.<br><br> 2. Moisten a lint-free cloth with distilled water. Wipe the top and sides of the tray platform and transport arm.<br><br> 3. Dry them with another lint-free cloth. 4.<br><br> Clean and dry the tray hook in the same manner. Tray Platform Transport Arm Tray Hook Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 329 Periodic Maintenance Cleaning the Tip-Locator Assembly Cleaning the Tip-Locator Assembly Clean the tip-locator assembly to remove glue deposits as well as any other type of contamination left from slides. 1.<br><br> Lift the top right cover of the analyzer. 2. Open the incubator cover.<br><br> Incubator Cover Periodic Maintenance Cleaning the Tip-Locator Assembly 2 330 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 3. Loosen the one thumbscrew that secures the tip-locator assembly cover to the tip-locator assembly. 4.<br><br> Remove the tip-locator cover, and set it aside. 5. Loosen the three thumbscrews on the tip-locator assembly.<br><br> Tip-Locator Assembly Cover Tip-Locator Assembly Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 331 Periodic Maintenance Cleaning the Tip-Locator Assembly 6. Turn over the tip-locator assembly. Use the edge of a spare slide to remove any glue deposits from the slide block area on the underside of the tip-locator assembly.<br><br> Discard the slide when you are finished. 7. Wipe the rest of the tip-locator assembly with a lint-free cloth moistened with distilled or deionized water.<br><br> Avoid touching electrical parts. Use light pressure only. 8.<br><br> Moisten a cotton swab with distilled or deionized water. Use the swab to clean the area under the tip-locator assembly (anywhere fluid has spilled). Avoid touching electrical parts.<br><br> 9. Moisten a cotton swab with distilled or deionized water. Use the swab to clean the top of the tip-locator assembly.<br><br> Tip-Locator Assembly TIP LOCATOR ASSEMBLY Clean area with swab Periodic Maintenance Cleaning the Tip-Locator Assembly 2 332 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 10. Allow the assembly to air-dry. Before replacing the tip-locator assembly and cover, continue with the remaining cleaning steps.<br><br> 11. Moisten a cotton swab with distilled or deionized water. Use the swab to clean the elevator.<br><br> 12. Place the transverse shuttle into the tip-locator assembly. 13.<br><br> Replace the tip-locator assembly, and hand tighten the three thumbscrews. 14. Replace the tip-locator cover, and hand tighten the one thumbscrew.<br><br> 15. Close the incubator cover. 16.<br><br> Close the top right cover of the analyzer. Elevator Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 333 Periodic Maintenance Cleaning the Tip-Locator Assembly 17. Touch the status console at the top of the monitor to bring up the error log screen showing the INITIALIZE target.<br><br> 18. Touch INITIALIZE to reset the modules. 19.<br><br> Run and evaluate quality control (QC) fluids to ensure that all the chemistries are performing correctly. RELEV ERR 14:13:12 VX.XX**250 OFF ON ER01A DOWN INITIALIZE UP SHUTDOWN MALFUNCTION ACTION ATTENTION TRANSIENT 8/17/93 11:00:30 Code: 3S7 MALFUNCTION 38 142 SCHEDULER * ENVIRONMENT TASK * interlock open 11:00:18 Code: 3S6 38 141 Apr 24 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > TouchUP or DOWN to move highlight bar. 8/17/93 MALFUNCTION SCHEDULER * ENVIRONMENT TASK * main cover interlock open Periodic Maintenance Cleaning the Cup Retainer 2 334 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Cleaning the Cup Retainer To clean the cup retainer: 1.<br><br> Lift the top left cover. 2. Moisten a lint-free cloth with distilled or deionized water, and wipe the top and bottom of the cup retainer.<br><br> 3. Dry it with another lint-free cloth. Cleaning the Touchscreen Monitor/Flat LCD Touchscreen Monitor To clean the touchscreen monitor: 1.<br><br> Touch an area of the touchscreen without buttons and continue touching. Cup Retainer Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 335 Periodic Maintenance Cleaning the Keypad Cover 2. Wipe the touchscreen and touchscreen frame with a lint-free cloth moistened with warm, soapy water, as shown.<br><br> CAUTION: Do not use solvents, ammonia, glass cleaners, or cleaning agents containing abrasives to clean the touchscreen. Figure 2-1. Cleaning the Touchscreen Monitor 3.<br><br> Wipe the touchscreen and touchscreen frame with a lint-free cloth moistened with distilled or deionized water to remove any soap residue. 4. If necessary, clean the touchscreen and touchscreen frame with a lint-free cloth dampened with 70% isopropyl alcohol-in-water solution.<br><br> 5. Discontinue touching the area of the touchscreen without buttons. 6.<br><br> Allow the touchscreen and touchscreen frame to air dry thoroughly. Cleaning the Keypad Cover Clean the keypad cover with a lint-free cloth moistened with distilled water. Backup QC, Config, and Calibration Data Follow the procedure found in Chapter 10, cOptions, d in the Operator 9s Manual.<br><br> Periodic Maintenance Cleaning the Sample-Metering Path 2 336 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Cleaning the Sample-Metering Path Examine the area under the path traveled by the sample metering proboscis. Look for signs of spilled or dried reagents or serum. To clean the sample metering path: 1.<br><br> Lift both top covers. 2. Moisten a lint-free cloth or cotton swab with distilled or deionized water.<br><br> 3. Clean the affected area. 4.<br><br> Dry the area thoroughly being careful not to leave any lint or cotton fibers behind. 5. Dispose of the cleaning materials in a biohazardous waste box.<br><br> Sample-Metering Proboscis Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 337 Periodic Maintenance Inspecting the Air Filter Inspecting the Air Filter The analyzer uses a washable air filter. You may want to have one or two spares so that you can rotate them after cleaning. To inspect and replace the air filter: 1.<br><br> Open the right front door of the analyzer. 2. Locate the air filter in the lower right corner.<br><br> 3. Look for signs of dust or dirt coating the exposed surface of the filter. This could compromise air flow into the analyzer and eventually lead to temperature errors.<br><br> 4. If the filter is dirty, remove it and replace it with a spare filter. The air filter is held in place by a hook-and-loop type fastening system.<br><br> 5. Clean the dirty filter. Remove heavy dust buildup by hand or brush, then wash the filter in water and allow it to air dry.<br><br> When dry, it will be ready to reuse when the current filter becomes dirty. IMPORTANT: Do not install a wet or damp filter. It could cause tem- perature problems by reducing air flow.<br><br> Allow filters to dry thoroughly before use. Air Filter Periodic Maintenance As-Required Maintenance 2 338 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 As-Required Maintenance To display the as-required maintenance procedures: 1. Touch PERIODIC MAINTENANCE on the Main Menu.<br><br> 2. Touch AS REQUIRED MAINTENANCE. Instructions for these periodic maintenance procedures together with additional as-required maintenance procedures follow.<br><br> 14:13:12 VX.XX**250 OFF ON PM00I REPLACE: 1. Salt pads in slide supply 1. 2.<br><br> Desiccant packs in slide supply 2. 3. Reflectometer lamp.<br><br> 4. Proboscis/sample metering tubing. CLEAN: 1.<br><br> Apr 24 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN PERIODIC MAINTENANCE - As Required Slide discard chutes. 2. Analyzer cabinetry.<br><br> 3. Dispense blade/slide path. Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 339 Periodic Maintenance Replacing Humidity Control Packs and Desiccant Packs Replacing Humidity Control Packs and Desiccant Packs Replace humidity control packs when humidity errors are posted for Slide Supply 1 or when directed to do so by your Customer Support Representative for troubleshooting purposes.<br><br> Replace desiccant packs when humidity errors are posted for Slide Supply 2 or when directed to do so by your Customer Support Representative for troubleshooting purposes. To replace humidity control packs and desiccant packs: 1. Open the right front door of the analyzer.<br><br> Humidity Control and Desiccant Pack Carriers Periodic Maintenance Replacing Humidity Control Packs and Desiccant Packs 2 340 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 2. Remove the carriers for the humidity control packs and desiccant packs, and discard the old pads and packs. 4 Pull down on the handle of each carrier to unlatch the carriers from the bottom of the slide supplies.<br><br> 4 Pull each carrier straight out of the analyzer. 3. Load new magnesium chloride humidity control packs for Slide Supply 1 (left side).<br><br> NOTE: The humidity control packs have no expiration date. They should be slightly moist, but not completely dry. Do not use them if they are extremely wet or completely dry.<br><br> 4. Load new desiccant (humidity control) packs for Slide Supply 2 (right side). Pull down, then out Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 341 Periodic Maintenance Replacing Humidity Control Packs and Desiccant Packs NOTE: There is a blue indicator in each desiccant pack wrapper that ensures the desiccant packs are good; the blue indicator turns pink if the desiccant packs are expired.<br><br> IMPORTANT: Do not interchange the carriers when you reinsert them. 5. Return both of the carriers to the slide supplies in the analyzer.<br><br> 6. Push up on the handle of each carrier to latch it against the bottom of the slide supplies. 7.<br><br> Close the front door. Slide Supply 2 3 Desiccant packs Slide Supply 1 3 Magnesium-Chloride Salt Pads Push in, then up Periodic Maintenance Changing the Reflectometer Lamp 2 342 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 Changing the Reflectometer Lamp Change the reflectometer lamp when the Help text for an error code directs you to do so or when directed by your Customer Support Representative. To change the reflectometer lamp, you will need a Reflectometer Lamp Extraction Tool, TL-3372.<br><br> 1. Open the right front door of the analyzer. NOTE: Use the lamp replacement label located on the inside of the slide processor front door as an instruction guide.<br><br> In the instructions that follow, (Illustration #) refers to the illustration number on the label. 2. Remove the cartridge-disposal box.<br><br> (Illustration 1) 3. Open the lamp safety door. (Illustration 2) The lamp safety door includes an interlock switch that removes power from the lamp.<br><br> CAUTION: The lamp is HOT. Wait 15 minutes for the lamp to cool. 4.<br><br> Press down Tab A to release the lamp socket latch C. (Illustration 3) Instructions Cartridge-Disposal Box Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 343 Periodic Maintenance Adjusting the Reflectometer Iris 5. Grasp the lamp socket, and remove it from the lamp base B.<br><br> (Illustration 4) 6. Disconnect the lamp socket connector 5A3J/P10. This allows the lamp socket assembly to be removed from the analyzer for easy access on a work surface.<br><br> 7. Remove the lamp using the extraction tool TL-3372, and discard the lamp. (Illustration 5) 8.<br><br> Grasp the new lamp using the plastic wrapper to prevent finger oil from contaminating the lamp surface. Insert the new lamp. (Illustration 6) IMPORTANT: Do not touch the lamp with your fingers.<br><br> Finger oil will affect system performance. 9. Return the lamp socket to its original position in the lamp base B.<br><br> (Illustration 7) 10. Press the latch C into the lock position. (Illustration 8) 11.<br><br> Reconnect the lamp socket connector 5A3J/P10. 12. Close the lamp safety door, and check that the interlock switch has engaged.<br><br> The lamp will illuminate. 13. Reinsert the cartridge disposal box.<br><br> 14. Allow the lamp to burn in or stabilize for at least 30 minutes. Then perform the reflectometer iris adjustment procedure that follows.<br><br> Adjusting the Reflectometer Iris 1. Touch DIAGNOSTICS on the Main Menu. DIAGNOSTICS May 19 XX 14:13:12 VX.XX**250 READY LAB COMP : TESTING COMPLETE SAMPLING OFF ON > Touch a target to select a function.<br><br> MD00A HELP RETURN SUBSYSTEM TESTS MEDS STANDALONE DIAGNOSTIC TESTS SETUP/ ADJUST HARDWARE AND CHEM INFO PERFORM- ANCE TESTS COMPLEX TESTS LAB COMP PROTOCOL ANALYZER REMOTE ENABLED Periodic Maintenance Adjusting the Reflectometer Iris 2 344 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 2. Touch SETUP/ADJUST. 3.<br><br> Touch REFLECTOMETER IRIS. DIAGNOSTICS - Setup/Adjustments 14:13:12 VX.XX**250 OFF ON SA00A LECTURE READ SAMPLE RATE/CM SLIDE CURRENT REFLECT- Apr 24 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN > Touch a target to select a function. METERING TRANSPORT IRIS OMETER SYNC CORRECTION FACTOR SETUP VALUES Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 345 Periodic Maintenance Adjusting the Reflectometer Iris 4.<br><br> Touch START after you have waited for the lamp to stabilize. 5. When cCenter the tool slide?<br><br> (Y/N) d is displayed on the prompt line, type cN d and press the Enter key on the keyboard. IMPORTANT: Do not type cY d at this prompt. Always type cN d to use the analyzer 9s internal reference slide.<br><br> 6. Touch START. The filter with the highest voltage reading will be displayed.<br><br> Note and record which filter is displayed. 7. Once the voltage reading is displayed, touch START again.<br><br> DIAGNOSTICS - Setup/Adjustment - Reflectometer Iris 14:13:12 VX.XX**250 OFF ON > Wait 30 minutes if a new lamp was installed. > Touch START to begin. SA10A WARNING: If a new lamp has been installed, the lamp must be allowed a 30 minute stabilizing period.<br><br> Failure to wait the allotted time could result in inaccurate results due to unstable lamp conditions. RETURN MAIN DIAG MENU START Apr 24 XX READY LAB COMP: TESTING COMPLETE SAMPLING HELP RETURN Periodic Maintenance Adjusting the Reflectometer Iris 2 346 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide Version 2.0 8. Move the iris control switch to the right or left as required to set the voltage according to the table below.<br><br> (Refer to illustrations 10 and 11 of the lamp replacement label located on the inside of the right front door as a guide.) You will be adjusting the voltage of the filter displayed in step 6 above. All other filter voltages will be less than the displayed filter. " Adjust the displayed filter to within the adjustment guidelines listed in Table 1.<br><br> " Verify that all filters fall within the verification guidelines listed in Table 2. If any of the filters are not within the verification guidelines, you may need to repeat the adjustment procedure. 9.<br><br> Touch DONE. Table 1. Filter Adjustment Guidelines Displayed filter wavelength Target voltage Any filter As high as possible up to 8.0 V Version 2.0 VITROS 250/350 Chemistry System Maintenance and Diagnostics Guide 2 347 Periodic Maintenance Adjusting the Reflectometer Iris 10.<br><br> The screen displays a

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